@ San Francisco State University
The Physiology of Pain & Tissue Damage
THE PROFESSOR - DR. MEGUMI FUSE
BACKGROUND
I grew up in Toronto, Canada, playing cello in high school. My passion for Biology came with its introduction in high school by my female Biology teacher. She rocked! I put my cello away and got my first research experience studying meal worms at U. of Toronto. I have been looking at the physiology of insects since!
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ACADEMICS
B.Sc. Zoology, University of Toronto (research mentor: Dr. John Machin)
M.Sc. Biology, York University (research mentor: Dr. Ken Davey)
Ph.D. Physiology, University of Toronto (research mentor: Dr. Ian Orchard)
NSERC Post Doctoral Research Fellow, University of Washington (research mentor: Dr. James Truman)
Professor, San Francisco State University
Director, Student Enrichment Opportunities Office
THE RESEARCHERS
LAB AND INSECT CARE
ALUMNI
2019
Imani Robinson, BS, SFSU
Genentech Foundation Scholar
Currently MS Candidate at SFSU, Márquez-Magaña lab (2020)
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Jennifer Kim, MS, SFSU
Thesis: DNA methylation as a candidate mechanism of nociceptive sensitization in the tobacco hornworm, Manduca sexta
Currently PhD Candidate at UBC (2019)
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Rebecca Melton, MS, SFSU
NIH RISE Scholar
Thesis: De novo transcriptome assembly from neural tissue of the tobacco hornworm Manduca sexta after injury-induced sensitization
Currently PhD Candidate at UCSD (2019)
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Rima Singh, MS, SFSU
Thesis: Immune response to tissue damage in the tobacco hornworm, Manduca sexta
Currently Research Associate II at Atreca (2019)
Pending: PhD Candidate at UC Irvine (2020)
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Andrew Mahoney, MS, SFSU
NIH RISE Scholar
Thesis: Developmental checkpoint identified during the last larval instar triggers developmental delays in the tobacco hornworm, Manduca sexta
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JC Herrera, BS, SFSU
Project: Allometry changes associated with tissue damage in M. sexta
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Sergio Ramirez, BS, SFSU
NIH MARC Scholar
Project: The role of protein synthesis in sensitization in M. sexta
Currently MS Candidate at SFSU/UCSF, Wendell Lim lab (2019; NIH RISE Scholar)
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2018
Manuel Rosero, MS, SFSU
NIH Bridge to PhD & Genentech Dissertation Scholar
Thesis: Juvenile Hormone is uncoupled from critical weight after imaginal disc damage in the holometabolous insect, Manduca sexta - PUBLICATION
Currently PhD Candidate at U Washington (2018)
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Alicia Rice, MS, SFSU
NIH RISE Scholar
Thesis: The role of the insect peptide, Pyrokinin, and opioids in modulating sensitization in the tobacco hornworm, Manduca sexta
Currently PhD Candidate at U Washington (2018)
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Janna Basahr, MS, SFSU
Thesis: Assessing systemic developmental responses to imaginal disc cell damage in
the hornworm, Manduca sexta - PUBLICATION
Currently PhD Candidate at UW-Madison (2018)
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Brenda Cisneros, MS, SFSU
NIH RISE Scholar
Thesis: The effects of imaginal disc damage on developmental delays and hemocyte populations
in the hornworm, Manduca sexta - PUBLICATION
Currently PhD Candidate at U Michigan (2017)
Erica Mai, MS, SFSU
NIH RISE Scholar
Thesis: The role of PTTH and ecdysteroids in the developmental delays associated with imaginal disc damage in Manduca sexta
Currently Clinical Lab Assistant at Zuckerberg SF General Hospital (2018)
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Kevin Lopez, BS, SFSU
Project: Phenotypic changes after repair from x-ray induced tissue damage in M. sexta
Currently Assistant Clinical Research Coordinator at UCSF (2020)
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Maribel Juarez, BS, SFSU
Project: Phenotypic changes after repair from x-ray induced tissue damage in M. sexta
Currently Medical Scribe at ScribeAmerica (2018)
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2017
Ben Abdon, BS, SFSU
Lab technician
Project: Developmental changes associated with imaginal disc damage in the insect, Manduca sexta - PUBLICATION
Currently PhD Candidate at U Michigan (2017)
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Rachel Bhaskar, MS, SFSU
Thesis: Immune Responses During Tissue Regeneration of Imaginal Discs in Manduca sexta
Currently Research Associate at Kite Pharma (2018)
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Ryan Marder, MS, SFSU
Thesis: Manduca sexta as a Model Host for Gut Microbiome and Invasion Studies
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Shreen Ghaleb, BS, SFSU
Project: Immune Responses During Tissue Regeneration of Imaginal Discs in M. sexta
Currently CEO and Founder of Collabful (2019)
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Jhony Zavaleta, BS, SFSU
Project: Body allometry after irradiation in M. sexta - PUBLICATION
Currently MS Candidate at SFSU, Rohlfs Lab (2019; NIH RISE Scholar, 2020; Genentech Foundation Scholar)
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Andrew Mahoney, BS, SFSU
Project: Body allometry after irradiation in M. sexta
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Phil Kanarsh, BS, SFSU
Project: Imaginal disc transplant methods in Manduca sexta
Currently Behavioral Technician at Autism Learning Partners (2018)
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2016
Dennis Tabuena, MS, SFSU
Thesis: A novel model for sensitization of nociception in the caterpillar, Manduca sexta - PUBLICATION1 / PUBLICATION2
Currently PhD Candidate at U of Washington (2016)
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Kimmie Fung, BS, SFSU
Project: Purge response in the hornworm, Manduca sexta
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Nick Farr, BS, SFSU
Project: Critical weight determination in the hornworm, Manduca sexta
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Ken Geraldi, BS, SFSU
Project: Response to capsaicin in the hornworm, Manduca sexta - PUBLICATION
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2015
Mitchell Lopez, MS, SFSU; PhD, UCSF
Thesis: Establishment and characterization of tissue specific response to irradiation damage in Manduca sexta
Currently in Biotech (2019)
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Michael Lindht, BS, SFSU
Student Helper​
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Allan Solis, BS, SFSU
Project: Electrophysiological characterization of nociception in an insect - PUBLICATION
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Michael Lee, BS, SFSU
Project: Developmental responses to imaginal disc ablation after injury
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Cody Burns, BS, SFSU
Project: Role of protein synthesis in nociceptive sensitization
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2014
Tiffany Hong, MS, SFSU
Thesis: Characterizing prothoracicotropic hormone response to X-ray tissue damage in Manduca sexta larvae
Currently PhD Candidate at UC Davis (2015)
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F Eric Arreola-Hernandez, BS, SFSU
Project: The role of cGMP in nociceptive sensitization in the hornworm, Manduca sexta - PUBLICATION
Currently PhD Candidate at UC Davis (2014)
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Tyler Deniston, BS, SFSU
Project: Long-term pain responses in an insect
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Tigran Makunts, BS, SFSU; PharmD, UCSD
Project: Apoptosis after x-ray tissue damage in an insect - PUBLICATION
Currently Clinical Pharmacology and Machine Learning Flow at the FDA (2020)
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2013
Tracy Wadsworth, MS, SFSU; MD, American University of the Carribean
Thesis: Characterizing ecdysis behaviors, neuromodulation, and circadian rhythmicity in the stick insect, Carasius morosus - PUBLICATION
Currently Pathology Resident Physician, U. Illinois at Chicago (2018)
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Louie Ramos, BS, SFSU
Project: Identifying a Developmental Delay Inducing Factor in the Tobacco Hornworm, Manduca sexta - PUBLICATION
Currently RA at UCSF (2017)
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Marie Stitt, BS, SFSU
Project: The role of insulin in delaying development in insects
Currently Quality Control Supervisor at BioMarin Pharmaceutical (2019)
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2012
David Canio, MS, SFSU
Thesis: Investigating the effects of brain removal on the behavior of ecdysis in Manduca sexta
Currently CA Regional Manager at IntraNerve Neuroscience (2019)
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Nicholas Silva, MS, SFSU; PhD, U. Michigan
Thesis: Systemic irradiation delays development by altering prothoracicotropic hormonal profiles to repair damaged tissue in the hornworm, Manduca sexta - PUBLICATION
Currently IRACDA fellow at UCSF (2019)
Roth Ea, MS, SFSU; Doctor of Podiatric Medicine, Rosalind Franklin U. of Medicine and Science
Thesis: The role of modulators in the regulation of ecdysis in the tobacco hornworm, Manduca sexta
Currently Resident Physician, Franciscan Health (2017)
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Ariel Aveo, BS, SFSU
Thesis: ETH activity during the intermolt period in Manduca sexta
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Vyron Tayag, BS, SFSU
Project: The role of the brain in ecdysis regulation in Manduca sexta
Currently Neurophysiologist at Elite Neurophysiology (2017)
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Cheikh Njie, BS, SFSU
Project: Apoptosis after tissue damage in Manduca sexta
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2011
Cleopa Omondi, MS, SFSU
Thesis: Characterizing the systemic responses to tissue damage in Manduca sexta
Currently MPH Student (2012)
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Marissa Zubia McMackin, MS, SFSU; PhD, UC Davis
Thesis: Thresholds of nociceptive sensitivity in Manduca sexta - PUBLICATION
Currently Adjunct Lecturer at at CSU San Marcos (2017)
Omid (Sayed) Miry, BS, SFSU; PhD, New York Medical College
Project: Determining hemocyte population changes after x-rays
Currently Postdoctoral fellow at Stanford (2017)
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Louie Ramos, BS, SFSU
Project: Developmental delays after x-ray damage in Manduca sexta
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Jared Geibig, BS, SFSU; MD Tufts University
Project: Regulation of cGMP levels during ecdysis in Manduca sexta
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Pablo Salinas, BS, SFSU
Project: Localization of peptides in the stick insect CNS
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2010
Laura Mendoza, MS, SFSU
Thesis: Determining the neurotransmitter that inhibits the CNS during ecdysis in the hornworm
Currently Elementary School Teacher (2012)
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Andrew Carriman, MS, SFSU
Thesis: Characterizing ecdysis behaviors in the stick insect, Carausius morosus - PUBLICATION
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Sabrina Bera, MS, SFSU
Thesis: Activation of the ecdysis neural network by the brain in Manduca sexta
Currently MD Intern in Washington DC (2017)
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Tyson Buis, BS, SFSU
Project: Electrophysiology of ecdysis motor programs in Manduca sexta
Currently Nurse Practitioner at Workit Health (2019)
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2009
Emily Merchasin, MS, SFSU
Thesis: Characterization of nociceptive sensitization in larval Manduca sexta
Currently in Biotech (2013)
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Kenichi Iwasaki, BS, SFSU; PhD, U. Michigan
Project: Pain responses in late larval Manduca sexta
Currently Postdoctoral fellow at U. Michigan (2015)
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Clelia Tommi, BS, SFSU
Project: Circadian rhythms in stick insects
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2008
Arianna Tamvacakis, MS, SFSU
Thesis: Ecdysis Triggering Hormone is active in intermolt tobacco hornworm
Currently Postdoctoral Fellow at University of Arkansas (2019)
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Allison Dias, BS, SFSU
Project: Measuring blood sugar levels in an insect
Currently in Biotech (2016)
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Rocio Diaz, BS, SFSU
Project: LK-like immunohistochemistry in Manduca sexta
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Ron Omino, BS, SFSU
Project: DH-like immunohistochemstry in Manduca sexta
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2007
Hani El Shawa, MS, SFSU
Thesis: The actions of Ecdysis Triggering Hormone on the ventral nerve cord during ecdysis in the tobacco hornworm, Manduca sexta
Currently CEO of Alpha Genomix Labs (2016)
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Arthur Salmon, MS, SFSU
Thesis: Ecdysis Triggering Hormone & synthetic analogs: Electrophysiological analysis of fictive ecdysis behaviors in the larval hornworm CNS
Currently OPS Manager at Neuralink (2018)
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Anna Drexler, MS, SFSU
Thesis: Molecular characterization and cell-specific expression of an ion transport peptide in the tobacco hornworm, Manduca sexta
Currently WHO Scientist in Geneva (2014)
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Ian Kimball, MS, SFSU
Thesis: Electromyographic analysis of ecdysis in the hornworm Manduca sexta
Currently PhD Candidate in UC Davis (2013)
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Myra Grace dela Pena, BS, SFSU
Project: Distribution of CHH peptides in Manduca sexta
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Alba Gutierrez, BS, SFSU
Project: Circadia rhythms in stick insects
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2005
Christina Harris, MS, SFSU
Thesis: Distribution of CHH in the tobacco hornworm, Manduca sexta
Postdoc at Tulane (2016)
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2003
Claudia Avala, MS, SFSU
Thesis: The effect of artificially prolonging ecdysis in the tobacco hornworm, Manduca sexta, on cGMP
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2002
Marilyn Asuncion-Uchi, MS, SFSU
Thesis: Regulation of ecdysis in the tobacco hornworm, Manduca sexta
Currently in Quality Control at Kaiser (2010)
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