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@ San Francisco State University
The Physiology of Pain & Tissue Damage
THE PROFESSOR - DR. MEGUMI FUSE
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BACKGROUND
I grew up in Toronto, Canada, playing cello in high school. My passion for Biology came with its introduction in high school by my female Biology teacher. She rocked! I put my cello away and got my first research experience studying meal worms at U. of Toronto. I have been looking at the physiology of insects since!
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ACADEMICS
B.Sc. Zoology, University of Toronto (research mentor: Dr. John Machin)
M.Sc. Biology, York University (research mentor: Dr. Ken Davey)
Ph.D. Physiology, University of Toronto (research mentor: Dr. Ian Orchard)
NSERC Post Doctoral Research Fellow, University of Washington (research mentor: Dr. James Truman)
Professor, San Francisco State University
Director, Student Enrichment Opportunities Office
THE RESEARCHERS
LAB AND INSECT CARE
ALUMNI
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2019
Imani Robinson, BS, SFSU
Genentech Foundation Scholar
Currently MS Candidate at SFSU, Márquez-Magaña lab (2020)
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Jennifer Kim, MS, SFSU
Thesis: DNA methylation as a candidate mechanism of nociceptive sensitization in the tobacco hornworm, Manduca sexta
Currently PhD Candidate at UBC (2019)
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Rebecca Melton, MS, SFSU
NIH RISE Scholar
Thesis: De novo transcriptome assembly from neural tissue of the tobacco hornworm Manduca sexta after injury-induced sensitization
Currently PhD Candidate at UCSD (2019)
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Rima Singh, MS, SFSU
Thesis: Immune response to tissue damage in the tobacco hornworm, Manduca sexta
Currently Research Associate II at Atreca (2019)
Pending: PhD Candidate at UC Irvine (2020)
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Andrew Mahoney, MS, SFSU
NIH RISE Scholar
Thesis: Developmental checkpoint identified during the last larval instar triggers developmental delays in the tobacco hornworm, Manduca sexta
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JC Herrera, BS, SFSU
Project: Allometry changes associated with tissue damage in M. sexta
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Sergio Ramirez, BS, SFSU
NIH MARC Scholar
Project: The role of protein synthesis in sensitization in M. sexta
Currently MS Candidate at SFSU/UCSF, Wendell Lim lab (2019; NIH RISE Scholar)
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2018
Manuel Rosero, MS, SFSU
NIH Bridge to PhD & Genentech Dissertation Scholar
Thesis: Juvenile Hormone is uncoupled from critical weight after imaginal disc damage in the holometabolous insect, Manduca sexta - PUBLICATION
Currently PhD Candidate at U Washington (2018)
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Alicia Rice, MS, SFSU
NIH RISE Scholar
Thesis: The role of the insect peptide, Pyrokinin, and opioids in modulating sensitization in the tobacco hornworm, Manduca sexta
Currently PhD Candidate at U Washington (2018)
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Janna Basahr, MS, SFSU
Thesis: Assessing systemic developmental responses to imaginal disc cell damage in
the hornworm, Manduca sexta - PUBLICATION
Currently PhD Candidate at UW-Madison (2018)
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Brenda Cisneros, MS, SFSU
NIH RISE Scholar
Thesis: The effects of imaginal disc damage on developmental delays and hemocyte populations
in the hornworm, Manduca sexta - PUBLICATION
Currently PhD Candidate at U Michigan (2017)
Erica Mai, MS, SFSU
NIH RISE Scholar
Thesis: The role of PTTH and ecdysteroids in the developmental delays associated with imaginal disc damage in Manduca sexta
Currently Clinical Lab Assistant at Zuckerberg SF General Hospital (2018)
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Kevin Lopez, BS, SFSU
Project: Phenotypic changes after repair from x-ray induced tissue damage in M. sexta
Currently Assistant Clinical Research Coordinator at UCSF (2020)
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Maribel Juarez, BS, SFSU
Project: Phenotypic changes after repair from x-ray induced tissue damage in M. sexta
Currently Medical Scribe at ScribeAmerica (2018)
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2017
Ben Abdon, BS, SFSU
Lab technician
Project: Developmental changes associated with imaginal disc damage in the insect, Manduca sexta - PUBLICATION
Currently PhD Candidate at U Michigan (2017)
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Rachel Bhaskar, MS, SFSU
Thesis: Immune Responses During Tissue Regeneration of Imaginal Discs in Manduca sexta
Currently Research Associate at Kite Pharma (2018)
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Ryan Marder, MS, SFSU
Thesis: Manduca sexta as a Model Host for Gut Microbiome and Invasion Studies
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Shreen Ghaleb, BS, SFSU
Project: Immune Responses During Tissue Regeneration of Imaginal Discs in M. sexta
Currently CEO and Founder of Collabful (2019)
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Jhony Zavaleta, BS, SFSU
Project: Body allometry after irradiation in M. sexta - PUBLICATION
Currently MS Candidate at SFSU, Rohlfs Lab (2019; NIH RISE Scholar, 2020; Genentech Foundation Scholar)
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Andrew Mahoney, BS, SFSU
Project: Body allometry after irradiation in M. sexta
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Phil Kanarsh, BS, SFSU
Project: Imaginal disc transplant methods in Manduca sexta
Currently Behavioral Technician at Autism Learning Partners (2018)
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2016
Dennis Tabuena, MS, SFSU
Thesis: A novel model for sensitization of nociception in the caterpillar, Manduca sexta - PUBLICATION1 / PUBLICATION2
Currently PhD Candidate at U of Washington (2016)
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Kimmie Fung, BS, SFSU
Project: Purge response in the hornworm, Manduca sexta
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Nick Farr, BS, SFSU
Project: Critical weight determination in the hornworm, Manduca sexta
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Ken Geraldi, BS, SFSU
Project: Response to capsaicin in the hornworm, Manduca sexta - PUBLICATION
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2015
Mitchell Lopez, MS, SFSU; PhD, UCSF
Thesis: Establishment and characterization of tissue specific response to irradiation damage in Manduca sexta
Currently in Biotech (2019)
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Michael Lindht, BS, SFSU
Student Helper​
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Allan Solis, BS, SFSU
Project: Electrophysiological characterization of nociception in an insect - PUBLICATION
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Michael Lee, BS, SFSU
Project: Developmental responses to imaginal disc ablation after injury
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Cody Burns, BS, SFSU
Project: Role of protein synthesis in nociceptive sensitization
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2014
Tiffany Hong, MS, SFSU
Thesis: Characterizing prothoracicotropic hormone response to X-ray tissue damage in Manduca sexta larvae
Currently PhD Candidate at UC Davis (2015)
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F Eric Arreola-Hernandez, BS, SFSU
Project: The role of cGMP in nociceptive sensitization in the hornworm, Manduca sexta - PUBLICATION
Currently PhD Candidate at UC Davis (2014)
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Tyler Deniston, BS, SFSU
Project: Long-term pain responses in an insect
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Tigran Makunts, BS, SFSU; PharmD, UCSD
Project: Apoptosis after x-ray tissue damage in an insect - PUBLICATION
Currently Clinical Pharmacology and Machine Learning Flow at the FDA (2020)
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2013
Tracy Wadsworth, MS, SFSU; MD, American University of the Carribean
Thesis: Characterizing ecdysis behaviors, neuromodulation, and circadian rhythmicity in the stick insect, Carasius morosus - PUBLICATION
Currently Pathology Resident Physician, U. Illinois at Chicago (2018)
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Louie Ramos, BS, SFSU
Project: Identifying a Developmental Delay Inducing Factor in the Tobacco Hornworm, Manduca sexta - PUBLICATION
Currently RA at UCSF (2017)
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Marie Stitt, BS, SFSU
Project: The role of insulin in delaying development in insects
Currently Quality Control Supervisor at BioMarin Pharmaceutical (2019)
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2012
David Canio, MS, SFSU
Thesis: Investigating the effects of brain removal on the behavior of ecdysis in Manduca sexta
Currently CA Regional Manager at IntraNerve Neuroscience (2019)
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Nicholas Silva, MS, SFSU; PhD, U. Michigan
Thesis: Systemic irradiation delays development by altering prothoracicotropic hormonal profiles to repair damaged tissue in the hornworm, Manduca sexta - PUBLICATION
Currently IRACDA fellow at UCSF (2019)
Roth Ea, MS, SFSU; Doctor of Podiatric Medicine, Rosalind Franklin U. of Medicine and Science
Thesis: The role of modulators in the regulation of ecdysis in the tobacco hornworm, Manduca sexta
Currently Resident Physician, Franciscan Health (2017)
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Ariel Aveo, BS, SFSU
Thesis: ETH activity during the intermolt period in Manduca sexta
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Vyron Tayag, BS, SFSU
Project: The role of the brain in ecdysis regulation in Manduca sexta
Currently Neurophysiologist at Elite Neurophysiology (2017)
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Cheikh Njie, BS, SFSU
Project: Apoptosis after tissue damage in Manduca sexta
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2011
Cleopa Omondi, MS, SFSU
Thesis: Characterizing the systemic responses to tissue damage in Manduca sexta
Currently MPH Student (2012)
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Marissa Zubia McMackin, MS, SFSU; PhD, UC Davis
Thesis: Thresholds of nociceptive sensitivity in Manduca sexta - PUBLICATION
Currently Adjunct Lecturer at at CSU San Marcos (2017)
Omid (Sayed) Miry, BS, SFSU; PhD, New York Medical College
Project: Determining hemocyte population changes after x-rays
Currently Postdoctoral fellow at Stanford (2017)
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Louie Ramos, BS, SFSU
Project: Developmental delays after x-ray damage in Manduca sexta
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Jared Geibig, BS, SFSU; MD Tufts University
Project: Regulation of cGMP levels during ecdysis in Manduca sexta
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Pablo Salinas, BS, SFSU
Project: Localization of peptides in the stick insect CNS
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2010
Laura Mendoza, MS, SFSU
Thesis: Determining the neurotransmitter that inhibits the CNS during ecdysis in the hornworm
Currently Elementary School Teacher (2012)
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Andrew Carriman, MS, SFSU
Thesis: Characterizing ecdysis behaviors in the stick insect, Carausius morosus - PUBLICATION
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Sabrina Bera, MS, SFSU
Thesis: Activation of the ecdysis neural network by the brain in Manduca sexta
Currently MD Intern in Washington DC (2017)
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Tyson Buis, BS, SFSU
Project: Electrophysiology of ecdysis motor programs in Manduca sexta
Currently Nurse Practitioner at Workit Health (2019)
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2009
Emily Merchasin, MS, SFSU
Thesis: Characterization of nociceptive sensitization in larval Manduca sexta
Currently in Biotech (2013)
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Kenichi Iwasaki, BS, SFSU; PhD, U. Michigan
Project: Pain responses in late larval Manduca sexta
Currently Postdoctoral fellow at U. Michigan (2015)
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Clelia Tommi, BS, SFSU
Project: Circadian rhythms in stick insects
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2008
Arianna Tamvacakis, MS, SFSU
Thesis: Ecdysis Triggering Hormone is active in intermolt tobacco hornworm
Currently Postdoctoral Fellow at University of Arkansas (2019)
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Allison Dias, BS, SFSU
Project: Measuring blood sugar levels in an insect
Currently in Biotech (2016)
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Rocio Diaz, BS, SFSU
Project: LK-like immunohistochemistry in Manduca sexta
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Ron Omino, BS, SFSU
Project: DH-like immunohistochemstry in Manduca sexta
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2007
Hani El Shawa, MS, SFSU
Thesis: The actions of Ecdysis Triggering Hormone on the ventral nerve cord during ecdysis in the tobacco hornworm, Manduca sexta
Currently CEO of Alpha Genomix Labs (2016)
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Arthur Salmon, MS, SFSU
Thesis: Ecdysis Triggering Hormone & synthetic analogs: Electrophysiological analysis of fictive ecdysis behaviors in the larval hornworm CNS
Currently OPS Manager at Neuralink (2018)
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Anna Drexler, MS, SFSU
Thesis: Molecular characterization and cell-specific expression of an ion transport peptide in the tobacco hornworm, Manduca sexta
Currently WHO Scientist in Geneva (2014)
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Ian Kimball, MS, SFSU
Thesis: Electromyographic analysis of ecdysis in the hornworm Manduca sexta
Currently PhD Candidate in UC Davis (2013)
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Myra Grace dela Pena, BS, SFSU
Project: Distribution of CHH peptides in Manduca sexta
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Alba Gutierrez, BS, SFSU
Project: Circadia rhythms in stick insects
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2005
Christina Harris, MS, SFSU
Thesis: Distribution of CHH in the tobacco hornworm, Manduca sexta
Postdoc at Tulane (2016)
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2003
Claudia Avala, MS, SFSU
Thesis: The effect of artificially prolonging ecdysis in the tobacco hornworm, Manduca sexta, on cGMP
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2002
Marilyn Asuncion-Uchi, MS, SFSU
Thesis: Regulation of ecdysis in the tobacco hornworm, Manduca sexta
Currently in Quality Control at Kaiser (2010)
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